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H&E-stained lung tissue slide showing anthracotic pigment deposits

Research output

Publications

Peer-reviewed work from the lab and its collaborators.

  1. Clinical and molecular correlates of digitally quantified anthracosis in lung tissue slides: utility of an automated quantitative workflow

    Fung LC , Joseph B , Ofori-Amanfo K , Lo T , Wang P , Trinder M , Barnabas G , Nikaido-Landry T , Durney CH , Tawara A , Ong S , Lam S , Meza R , Myers R , Lockwood WW , McGuire A , Naso JR , Lim EL

    Journal of Pathology: Clinical Research · 2026

  2. EGFR Dysregulation and Climate Change: Insights into Pollution-Promoted Lung Cancer

    Nikaido-Landry T , Zhang S , Lim EL

    Philosophical Transactions of the Royal Society B · 2026

  3. Gene expression signatures of shortened-telomere-associated fibrotic interstitial lung disease

    Naso JR , Sosa C , Schefter LE , Petersen MJ , Nikaido-Landry T , Lim E , Ferrer A , Patnaik MM , Scott JP , Halling KC , Roden AC

    Human Pathology · 2026

  4. Nasal budesonide mitigates air pollution effects in adults with allergic rhinitis: A randomized trial

    Halbe E , Rider CF , Yuen ACY , Johal P , Hashimoto A , MacIsaac JL , Dever K , Schwartz C , Lau KSK , Lim EL , Afshar T , Jude MS , Konwar C , Kobor MS , Carlsten C

    Annals of Allergy, Asthma & Immunology · 2026

  5. Rethinking the microenvironment's role in chemical-induced malignancy

    Bisson WH , Currie RA , Lim EL , Mlynarczyk C , Tokar EJ , Colacci A , Colacino JA

    Toxicological Sciences · 2026

  6. The Data Science at the Interface of Air Pollution and Lung Health: Towards Precision Health

    Ofori-Amanfo K , Dustin M , Lim EL

    Annual Review of Biomedical Data Science · 2026

  7. Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER

    Lucas O , Ward S , Zaidi R , Bunkum A , Frankell AM , Moore DA , Hill MS , Liu WK , Marinelli D , Lim EL , Hessey S , Naceur-Lombardelli C , Rowan A , Purewal-Mann SK , Zhai H , Dietzen M , Ding B , Royle G , Aparicio S , McGranahan N , Jamal-Hanjani M , Kanu N , Swanton C , Zaccaria S

    Nature Genetics · 2025

  8. DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution

    Gimeno-Valiente F , Castignani C , Cadieux EL , Mensah NE , Liu X , Chen K , Chervova O , Karasaki T , Weeden CE , Richard C , Lai S , Martínez-Ruiz C , Lim EL , Frankell AM , Watkins TBK , Stavrou G , Usaite I , Lu WT , Marinelli D , Saghafinia S , Wilson GA , Dhami P , Vaikkinen H , Steif J , Veeriah S , Hynds RE , Hirst M , Hiley C , Feber A , Deniz Ö , Jamal-Hanjani M , McGranahan N , Beck S , Demeulemeester J , Tanić M , Swanton C , Van Loo P , Kanu N

    Nature Genetics · 2025

  9. The Nature and Nurture of Carcinogenesis

    Lim EL , DeGregori J

    Cancer Discovery · 2025

  10. Woodsmoke and diesel exhaust: Distinct transcriptomic profiles in the human airway epithelium

    Huff RD , Rider CF , Lo T , Hardy KI , El-Bittar N , Ryu MH , Carlsten C , Lim EL

    Ecotoxicology and Environmental Safety · 2025

  11. Lung adenocarcinoma promotion by air pollutants

    Hill W* , Lim EL* , Weeden CE* , Lee C , Augustine M , Chen K , Kuan FC , Marongiu F , Evans EJ , Moore DA , Rodrigues FS , Pich O , Bakker B , Cha H , Myers R , van Maldegem F , Boumelha J , Veeriah S , Rowan A , Naceur-Lombardelli C , Karasaki T , Sivakumar M , De S , Caswell DR , Nagano A , Black JRM , Martínez-Ruiz C , Ryu MH , Huff RD , Li S , Favé MJ , Magness A , Suárez-Bonnet A , Priestnall SL , Lüchtenborg M , Lavelle K , Pethick J , Hardy S , McRonald FE , Lin MH , Troccoli CI , Ghosh M , Miller YE , Merrick DT , Keith RL , Al Bakir M , Bailey C , Hill MS , Saal LH , Chen Y , George AM , Abbosh C , Kanu N , Lee SH , McGranahan N , Berg CD , Sasieni P , Houlston R , Turnbull C , Lam S , Awadalla P , Grönroos E , Downward J , Jacks T , Carlsten C , Malanchi I , Hackshaw A , Litchfield K , DeGregori J , Jamal-Hanjani M , Swanton C

    Nature · 2023

  12. Pervasive chromosomal instability and karyotype order in tumour evolution

    Watkins TBK* , Lim EL* , Petkovic M , Elizalde S , Birkbak NJ , Wilson GA , Moore DA , Grönroos E , Rowan A , Dewhurst SM , Demeulemeester J , Dentro SC , Horswell S , Au L , Haase K , Escudero M , Rosenthal R , Al Bakir M , Xu H , Litchfield K , Lu WT , Mourikis TP , Dietzen M , Spain L , Cresswell GD , Biswas D , Lamy P , Nordentoft I , Harbst K , Castro-Giner F , Yates LR , Caramia F , Jaulin F , Vicier C , Tomlinson IPM , Brastianos PK , Cho RJ , Bastian BC , Dyrskjøt L , Jönsson GB , Savas P , Loi S , Campbell PJ , Andre F , Luscombe NM , Steeghs N , Tjan-Heijnen VCG , Szallasi Z , Turajlic S , Jamal-Hanjani M , Van Loo P , Bakhoum SF , Schwarz RF , McGranahan N , Swanton C

    Nature · 2020

  13. MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia

    Lim EL , Trinh DL , Ries RE , Wang J , Gerbing RB , Ma Y , Topham J , Hughes M , Pleasance E , Mungall AJ , Moore R , Zhao Y , Aplenc R , Sung L , Kolb EA , Gamis A , Smith M , Gerhard DS , Alonzo TA , Meshinchi S , Marra MA

    Journal of Clinical Oncology · 2017

  14. Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients

    Lim EL , Trinh DL , Scott DW , Chu A , Krzywinski M , Zhao Y , Robertson AG , Mungall AJ , Schein J , Boyle M , Mottok A , Ennishi D , Johnson NA , Steidl C , Connors JM , Morin RD , Gascoyne RD , Marra MA

    Genome Biology · 2015

  15. T3DB: a comprehensively annotated database of common toxins and their targets

    Lim E , Pon A , Djoumbou Y , Knox C , Shrivastava S , Guo AC , Neveu V , Wishart DS

    Nucleic Acids Research · 2009