Environmental exposures have been associated with the incidence of age-related illnesses such as cancer, cardiovascular disease, impaired cognitive function, metabolic dysregulation. However, how most environmental exposures, such as pollution, contribute to disease is still unclear.

The Lim Lab investigates how environmental pollutants shape the genomics, transcriptomics and epigenomics of cells to transform normal tissues into disease states.

We utilize a multi-omic approach to study samples from cancer patients and from individuals who have been exposed to pollution.

Our lab is part of the Department of Biochemistry and Molecular Biology and the Edwin S.H. Leong Centre for Healthy Aging. We are located within the Life Sciences Institute at the University of British Columbia, and are affiliated with Canada's Michael Smith Genome Sciences Centre.